PHAR 623 IPC V - Gastrointestinal/Nutrition

The concepts of pathophysiology, medicinal chemistry, pharmacology, and pharmacotherapy are applied to the management of patients with gastrointestinal or nutritional disease. The course will introduce the pathophysiology of a particular disease condition, followed by the respective drugs or drug classes emphasizing mechanisms of action, pharmacokinetics, and effects on various organ systems, toxicity profiles, contraindications, and drug-drug interactions. Pharmacotherapeutics will be taught in a sequential and integrative manner to link principles of medicinal chemistry coupled with the pharmacology of the drugs used in the corresponding disease and the pathophysiology and therapeutic principles in clinical practice. The clinical presentation, course of illness, assessment of patient, and epidemiology of disease as well as treatment and preventative measures using pharmacologic and non-pharmacologic approaches will be reviewed. This will enable students to correlate the knowledge from both basic sciences and clinical sciences and to develop rational therapeutic recommendations to various healthcare providers and patients.