PHAR 625 IPC VI - Infectious Disease

The concepts of microbiology, pathophysiology, medicinal chemistry, pharmacology, and pharmacotherapy are applied to the management of patients with infectious diseases. The course will review microbiology of important pathogens and will present the respective anti-infective agents or the classes emphasizing their structure, activity, and spectrum relationship, mechanisms of action, clinical pharmacokinetics including penetration to the sites of infection, toxicity profiles, contraindications, and drug interactions.  Pharmacotherapeutics will be taught in a sequential and integrative manner to tie in the knowledge and concepts from pharmacology, medicinal chemistry, coupled with the spectrums of the anti-infectives used in the corresponding infectious diseases, the pathophysiology and therapeutic principles in clinical practice. The epidemiology of infectious diseases, clinical presentations, courses of illness, assessment of patients, and as well as treatment and preventive measures using pharmacologic and non- pharmacologic approaches will be reviewed. This will enable students to relate the knowledge from both basic sciences and clinical sciences and to develop rational therapeutic recommendations to various healthcare providers and patients.